| 产品名称 | ALK1 Kinase Assay Kit - Kinase(s) |
| 产品货号 | 79549 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 96 reactions |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Background: ALK1, also known as activin receptor-like kinase 1 (ACVRL1) is a type I receptor from the TGF-β family of transmembrane serine/threonine kinases. Mutation of ALK1 is seen to play a role in pulmonary arterial hypertension (PAH), Osler-Weber-Rendu syndrome, and vascular smooth muscle cell development.
Description: The ALK1 Kinase Assay Kit is designed to measure ALK1 kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent. The ALK1 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant ALK1 enzyme, ALK1 substrate, ATP and kinase assay buffer for 100 enzyme reactions. Materials Required But Not Provided: ADP-Glo® Kinase Assay (Promega #V6930) Dithiothreitol (DTT, 1 M; optional) Microplate reader capable of reading luminescence Adjustable micropipettor and sterile tips 30°C incubator Synonym(s): activin receptor-like kinase 1, ACVRL1
Supplied As: The ALK1 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant ALK1 enzyme, ALK1 substrate, ATP and kinase assay buffer for 100 enzyme reactions.
Format:
Storage / Stability: Up to 6 months when stored as recommended
Application(s): Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications
Reference(s): Cunha, Sara I., and Kristian Pietras. “ALK1 as an Emerging Target for Antiangiogenic Therapy of Cancer.” Blood 117(26): 6999–7006 (2011).
Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
|
| 产品资料 |
