| 产品名称 | 14-3-3 epsilon Protein, His-tag (Mouse) - Kinase(s) |
| 产品货号 | 79026 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 20 μg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Mouse
Host Species: Sf9 insect cells using baculovirus
MW: 33 kDa
Genbank #: NM_009536
Tag(s): N-terminal His tag
a.a: Full length
Background: 14-3-3 epsilon, also known as tyrosine 3-mono-oxygenase/tryptophan 5-monooxygenase activation protein is a member of the 14-3-3 family. 14-3-3 epsilon has been reported to be involved in heat shock transcription factor 1 (HSF1) and extracellular signal regulated protein kinase (ERK) pathways (1). 14-3-3epsilon interaction with the deubiquitinating enzyme UBPY, also known as USP8, regulates cargo sorting and membrane traffic at early endosomes. Association of 14-3-3 epsilon, HSF1 with ERK during heat shock may modulate the amplitude of the response and control the termination of HSP expression on resumption of growth conditions (2).
Description: Mouse 14-3-3 epsilon Protein, GenBank Accession No. NM_009536, full length, with N-terminal His tag, expressed in Sf9 insect cells using baculovirus. MW = 33 kDa.
Synonym(s): Ywhae; AU019196
Formulation: 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
Storage / Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Application(s): Western blot
Reference(s): 1. Wang, X. et al: Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress. J. Biol. Chem. 2004; 279(47):49460-9.
2. Mizuno, E. et al: 14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase. Exp Cell Res. 2007; 313(16):3624-34. Scientific Category: Kinase
Product Type: Protein
Data shown is lot-specific. Contact us for specific information on other lots.
Quality Assurance
|
| 产品资料 |
