产品名称 BAY-60-7550 - Phosphodiesterase - Inhibitors / Activators
产品货号 27215
产品价格 现货询价,电话:010-67529703
产品规格 5 mg
产品品牌 bpsbioscience
产品概述
产品详情
MW: 476.6 Da
CAS Registry #: 439083-90-6
Formula: C27H32N4O4
Description:
BAY-60-7550 is a potent inhibitor of PDE2. It is more selective for PDE2 than PDE1 by 50-fold. Similarly, it is 100-fold more selective for PDE4B, PDE5B, PDE7B, PDE8A, PDE9A, PDE10A, and PDE11A.
Purity:

≥95% by HPLC

Biological Activity:
BAY-60-7550 inhibits PDE2 with an IC50 of 2.0 nM in bovine, and 4.7 nM in humans.
Solubility:
Soluble in ethanol, DMSO and DMF, purged with an inert gas. Solubility in ethanol, DMSO and DMF is ~10 mg/ml.
Format:
A crystalline solid.
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s):
1. Boess, F.G., et al., Neuropharmacology. 2004; 47: 1081-1092.
2. Masood, A., et al., J. Pharmacol. Exp. Ther. 2008; 326(2): 369-379.
3. Rutten, K., et al., Neuropsychopharmacology. 2009; 34: 1914-1925.
Scientific Category:
PDE
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.

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Product Datasheets

27215_Lot120607.pdf

产品资料