产品名称 | BAY-60-7550 - Phosphodiesterase - Inhibitors / Activators |
产品货号 | 27215 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 5 mg |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
MW: 476.6 Da
CAS Registry #: 439083-90-6
Formula: C27H32N4O4
Description: BAY-60-7550 is a potent inhibitor of PDE2. It is more selective for PDE2 than PDE1 by 50-fold. Similarly, it is 100-fold more selective for PDE4B, PDE5B, PDE7B, PDE8A, PDE9A, PDE10A, and PDE11A.
Purity: ≥95% by HPLC Biological Activity: BAY-60-7550 inhibits PDE2 with an IC50 of 2.0 nM in bovine, and 4.7 nM
in humans.
Solubility: Soluble in ethanol, DMSO and DMF, purged with an inert gas. Solubility in ethanol,
DMSO and DMF is ~10 mg/ml.
Format: A crystalline solid.
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s): 1. Boess, F.G., et al., Neuropharmacology. 2004; 47: 1081-1092.
2. Masood, A., et al., J. Pharmacol. Exp. Ther. 2008; 326(2): 369-379. 3. Rutten, K., et al., Neuropsychopharmacology. 2009; 34: 1914-1925. Scientific Category: PDE
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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产品资料 |