| 产品名称 | GDC-0941 - Kinase - Inhibitors / Activators |
| 产品货号 | 27000 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 25 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 513.6 Da
CAS Registry #: 957054-30-7
Formula: C23H27N7O3S2
Description: GDC-0941, also known as Pictilisib, is a phosphatidylinositol 3-kinase (PI3K) inhibitor
Synonym(s): GDC-0941, Pictilisib
Purity: ≥99% by HPLC. Biological Activity: GDC-0941 against p110a IC50=0.003µM. The IC50 for inhibiting cell proliferation in PC3 (prostate cancer) or U87MG (glioma) cells is 0.28 µM and 0.95 µM, respectively.
Solubility: Soluble in DMSO at 66 mg/ml; very poorly soluble in ethanol; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 µg
Format: Solid
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s): 1. Folkes, A.J. et al. J. Med. Chem. 51: 5522-5532 (2008)
2. Yao, E. et al. Clin. Cancer Res. 15: 4147-4156 (2009) Scientific Category: Kinase
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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