INCB024360 analog is an orally available hydroxyamidine and inhibitor of indoleamine 2,3- dioxygenase (IDO1), with an IC50 of 10 nM. It shows little activity against other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO). INCB024360 analog displays potential immunomodulating and antineoplastic activities.
| 产品名称 | INCB024360 Analog - Immunotherapy - Inhibitors / Activators |
| 产品货号 | 27338-1 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 271.6 Da
CAS Registry #: 914471-09-3
Formula: C9H7ClFN5O2
Description: Synonym(s): 4-[(3-chloro-4-fluoroanilino)-nitrosomethylidene]-1,2,5-oxadiazol-3-amine, IDO inhibitor
Purity: ≥98%
Biological Activity: INCB024360 analog has been reported to restore and increase the proliferation of
various immune cells including dendritic cells, NK cells, and T cells in vitro and in vivo.
Solubility: Soluble in DMSO.
Format: White powder
Storage / Stability: Store as supplied at or below -20°C for up to 2 years. Stable in DMSO at
-80°C for up to 6 months.
Reference(s): 1. Koblish, HK., et al., Molec. Cancer Therapeutics. 2010; 9: 489-498. Scientific Category: Immunotherapy
Product Type: Inhibitors/Activators
Data shown is lot-specific. Contact us for specific information on other lots.
|
| 产品资料 |
