产品名称 | RediSolution™ (+)-JQ1 - Bromodomain - Inhibitors / Activators |
产品货号 | 27403 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 1 mg |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
MW: 457.0 Da
CAS Registry #: 1268524-70-4
Formula: C23H25ClN4O2S
Description: (+)-JQ1 is a specific inhibitor of the BET family of acetyl-lysine recognition motifs, including the BRD2, BRD3, BRD4 and BRDT bromodomains.
Synonym(s): BET inhibitor, Bromodomain inhibitor
Purity: ≥95% by HPLC Supplied As: 10 mM solution in anhydrous DMSO
Biological Activity: (+)-JQ1 has been shown to inhibit BRD4 (BD1) with a Kd of 50 nM, and BRD4 (BD2) with a Kd of 90 nM.
Format: DMSO solution
Storage / Stability: Store at –20°C and avoid multiple freeze-thaw cycles to prevent decomposition.
Reference(s): Filippakopoulos P., et al. Nature. 468(7327):1067-73 (2011). Application Reference:
Warning(s): Avoid freeze/thaw cycles.
Scientific Category: Bromodomain
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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产品资料 |