Aliskiren Hydrochloride is an orally active, synthetic nonpeptide Renin inhibitor that has been shown to work as an antihypertensive.

≥95% by HPLC

Aliskiren is one of the most potent renin inhibitors with an IC50 value of 0.6 nM.

Soluble in methanol and chloroform.

A crystalline solid.

Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

1. Wood, JM, et al., Biochem Biophys Res Commun. 2003 Sep 5;308(4):698-705.
2. Gradman, AH, et al., Circulation. 2005 Mar 1;111(8):1012-8.

Protease

Inhibitor