| 产品名称 | AGK2 - Inhibitors / Activators - Deacetylase(s) |
| 产品货号 | 27228 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 5 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 434.3 Da
CAS Registry #: 304896-28-4
Formula: C23H13Cl2N3O2
Description: AGK2 is a selective, cell-permeable inhibitor of SIRT2. It has minimal effects SIRT1 and SIRT3 at 10-fold higher levels compared to SIRT2. Useful for studing SIRT2 in neurodegeneration and aging, as well as cell cycle progression and tumorigenesis.
Purity: ≥98% by HPLC Biological Activity: AGK2 inhibits SIRT2 with an IC50 value of 3.5 µM.
Solubility: Soluble in DMSO and DMF purged with an inert gas. Solubility is approximately 1
mg/ml in DMSO and approximately 3 mg/ml in DMF.
Format: A crystalline solid.
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s): Outeiro, T.F., et al., Science. 2007;317:516-519.
Scientific Category: HDAC
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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