| 产品名称 | NcoR2 (SMRT), GST-tag - Enzymes - Deacetylase(s) |
| 产品货号 | 50020 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 50 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 39 kDa
Genbank #: NM_006312
Tag(s): N-terminal GST-tag
a.a: 395–489
Background: NcoR2 , nuclear receptor corepressor, are transcriptional corepressors that play an essential role in the regulation of development and metabolism. The interaction of HDAC3 with the deacetylase activation domain , DAD, of NCOR2/SMRT is required for activation of the otherwise inert deacetylase.
Description: Human NCOR2/SMRT, DAD domain, a.a. 395-489, GenBank Accession No. NM_006312, N-terminal GST-tag, MW= 39 kDa, expressed in E. coli system. Source: E. coli. Purity: > 60% by SDS-PAGE.
UniProt Q9Y618
Synonym(s): nuclear receptor corepressor 2, Silencing mediator of retinoic acid and thyroid hormone receptor, TRAC-1, SMRT, NcoR2
Formulation: 50 mM Tris-HCl, pH 8.0, 138 mM NaCl, 20 mM glutathione, and 10%
glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): Codina, A. et al., Proc. Natl. Acad. Sci. USA, 102, 6009-6014, (2005)
Warning(s): Avoid freeze/thaw cycles.
Scientific Category: Deacetylase
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
Quality Assurance |
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