| 产品名称 | Droxinostat - Deacetylase(s) |
| 产品货号 | 27620-2 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 25 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 243.7 Da
CAS Registry #: 99873-43-5
Formula: C11H14ClNO3
Target: HDAC6, HDAC8
Background: Droxinostat has shown a potent action against HDAC3, HDAC6, and HDAC8 which are pyrimidyl-hydroxamic acid-dependent histone deacetylases. Droxinostat shows a significant action on gene transcription hence controlling tumor progression. The cells resistant to the caspase mediated apoptotic pathway get sensitized by Droxinostat, hence proving an active agent of introducing death in cancerous cells.
Synonym(s): NS 41080; 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
Purity: ≥98% by HPLC Solubility: Soluble in DMSO
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. Reference(s): 1. Bijangi-Vishehsaraei K, et al. Mol Cell Biochem. 2010 Sep;342(1-2):133-42.
2. Wood TE, et al. Mol Cancer Ther. 2010 Jan;9(1):246-56. Scientific Category: Deacetylase Inhibitor
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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