Mouse secreted CD137, also known as Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, and ILA, GenBank Accession No. NM_001561, a.a. 24-187, fused at the Cterminus to the Fc portion of mouse IgG2a, with a C-terminal AviTag^TM expressed in a HEK293 cell expression system. MW = 46.7 kDa (monomer). This protein runs at a higher MW by SDSPAGE due to glycosylation.

P20334

Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, ILA, 4-1BB

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

At least 6 months at –80°C.

Useful for studying protein binding and screening small molecules.

1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659.
2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to 100 μg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy/Cell Surface Receptor

Recombinant Protein