| 产品名称 | I-BET-762 - Inhibitors / Activators - Bromodomain(s) |
| 产品货号 | 27630-1 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 5 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 423.9 Da
CAS Registry #: 1260907-17-2
Formula: C22H22ClN5O2
Target: BET
Background: Bromodomains have an important role in the targeting of chromatin-modifying enzymes to specific sites, including methyltransferases, HATs and transcription factors and regulate diverse biological processes from cell proliferation and differentiation to energy homeostasis and neurological processes.
Description: I-BET-762 is a small molecule inhibitor of the BET family of bromodomaincontaining
proteins. It has been shown to bind to the acetylated lysine recognition motifs on the
bromodomain of BET proteins. This binding prevents the interaction of between BET proteins
and acetylated histone peptides.
Synonym(s): 2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide
Solubility: Soluble in Water
Storage / Stability: Powder is stable at -20°C for up to 3 years. Re-suspended powder is stable
at -80°C for up to 6 months.
Reference(s): Nicodeme E, et al. Nature. 2010 Dec 23;468 (7327):1119-23.
Scientific Category: Bromodomain Inhibitor
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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| 产品资料 |
