| 产品名称 | Donepezil HCl - Metabolic Enzymes |
| 产品货号 | 27619-1 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 1 g |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 416 Da
CAS Registry #: 120011-70-3
Formula: C24H30ClNO3
Target: acetylcholinesterase (AChE)
Background: Donepezil HCl is a piperidine-class AChE inhibitor containing an N-benzylpiperdine and an indanone moiety, which confers it a longer and more selective action against AchE as compared to BuChE (IC50: 7.4 µM). Donepezil HCl has been shown to improve cognitive function of mild to severe moderate AD patients and exhibits excellent tolerability without hepatotoxicity.
Synonym(s): Aricept; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one hydrochloride
Solubility: Soluble in DMSO
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. Reference(s): Birks, J., Harvey, R.J . Cochrane Database Syst Rev. 2006 Jan 25;(1):CD001190.
Scientific Category: Metabolism
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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