CD38, a differentiation antigen of B lymphocytes, is a type II integral membrane protein. It is also known as ADP-ribosyl cyclase and nicotinamide adenine dinucleotide (NAD) glycohydrolase. Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in various cells, including pancreatic β cells. The major enzymatic activity of CD38 is the hydrolysis of NAD. CD38 is a prognostic biomarker for acute B lymphoblastic leukemia.
| 产品名称 | CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) - Assay kits - Immunotherapy |
| 产品货号 | 79672 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 384 Reactions |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Background: Description: The CD38 Inhibitor Screening Assay Kit (Hydrolase Activity) is designed to measure the glycohydrolase activity of CD38 for screening and profiling applications.
Materials Required But Not Provided: Adjustable micropipettor and sterile tips Fluorescent microplate reader Rotating or rocker platform Synonym(s): cluster of differentiation 38, cyclic ADP ribose hydrolase, activity assay kit
Supplied As: The CD38 assay kit comes in a convenient high-throughput 384-well format, with purified recombinant CD38 enzyme, its substrate N6-etheno-NAD (ε-NAD), and CD38 assay buffer for 384 enzyme reactions.
Format:
Instructions for use: See assay kit data sheet for detailed protocol.
Storage / Stability: Up to 6 months from date of receipt, when stored as recommended.
Application(s): Great for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s): Wei, W., et al., World J. Biol. Chem. 2014. 5(1):58-67.
Warning(s): Avoid multiple freeze/thaw cycles.
Scientific Category: Immunotherapy
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
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