Human CD150, Fc fusion protein, also known as signaling lymphocytic activation molecule (SLAM) or SLAMF1. GenBank Accession No. NM_003037, a.a. 21-237 expressed in a HEK293 cell expression system. This protein is fused at the C-terminus to the Fc region of human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 53 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Signaling lymphocytic activation molecule, SLAM, SLAMF1

8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

At least 6 months at –80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Useful for studying protein binding and for screening small molecules and antibodies.

1. Tatsuo, H. et al., Journal of Virology. 2001; 75: 5842-5850.

2. Sidorenko, S. et al., Nature Immunology. 2003; 4: 19-24.

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Fc Fusion Protein