A peptide substrate for Histone 3, K4,K9 methyltransferases. The peptide corresponds to residues 1-21 of histone H3.

P68431

Histone 3.1, HIST1H3E

≥95% by HPLC

800 µM solution in water (200 µl)

aqueous solution

≥ 12 months at -20°C or -70°C

Useful as a substrate for methyltransferase (at K4 and K9) or acetyltransferase (at K9 and K14) family assays and for screening small molecular inhibitors of Histone 3 (K4,K9) methyltransferases for drug discovery.

Application Reference(s):
Differential mode of antimicrobial actions of arginine-rich and lysine-rich histones against Gram-positive Staphylococcus aureus (2013)

Avoid freeze/thaw cycles.

ARTKQTARKSTGGKAPRKQLA

Methyltransferase

Substrate