Mouse secreted Programmed Cell Death 1 Ligand 1 (PD-L1)-Fc fusion protein, also known as CD274 and B7 homolog 1 (B7- H1), GenBank Accession No. NM_021893, a.a. 18-238, fused at the C-terminus to the Fc portion of mouse IgG2a and with a Cterminal Avi-tag, expressed in a HEK293 cell expression system. This protein was biotinylated using AviTag™ technology. MW = 54 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation.

Q9EP73

Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7-H1)

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Aqueous buffer solution

At least 6 months at –80°C.

Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.

1. Freeman, G.J., et al., J Exp Med. 2000; 192(7):1027-34.
2. Dong, H., et al., Nat Med. 1999; 5(12):1365-9.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Fc Fusion Protein