Mouse secreted Programmed Cell Death 1 (PD-1)-Fc fusion protein, also known as CD279, PDCD1, and SLEB2, GenBank Accession No. NM_008798, a.a. 25-167, fused at the C-terminus to the Fc portion of mouse IgG2a and with a C-terminal Avi-tag, expressed in a HEK293 cell expression system. This protein was biotinylated using AviTagTM technology. MW = 45 kDa. Note: this protein runs at an apparent higher molecular weight due to glycosylation.

Q02242

Programmed Cell Death 1, CD279, PDCD1, SLEB2

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

Aqueous buffer solution

At least 6 months at –80°C.

Useful for the study of protein-protein interaction and in vitro and in vivo protein function studies.

1. Agata, Y., et al., Internat. Immunol. 1996; 8(5): 765-772.

2. Freeman, G.J. et al., J. Exp. Med. 2000; 192(7): 1027-1034.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Fc Fusion Protein