Fc region of human immunoglobulin G1 (IgG1) protein, also known as Il-4, GenBank Accession No. P01857, a.a. 100-330, expressed in an HEK293 cell expression system. MW = 27 kDa.

IgG1, Fc

8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol

At least 6 months at –80°C. Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Useful as an isotype control for studies using human IgG1 antibodies.

1. Furst, DE, et al., Journal of Rheumatology. 1999 Feb; 30(10):2123-2126.

2. Sondermann, P., et al., Nature. 2000 Jul; 406: 267-273.

HiP™ indicates a high purity protein with ≥90% purity as measured by gel filtration.

Immunotherapy

Protein